In fact, the rarest eye color in the world is likely violet or red. Less than 1% of the world’s population has them, making them rarer than blue, hazel, amber, grey, or green eyes. It is important to note that natural purple eyes are extremely rare. In some cases, the lack of pigmentation in the eyes can result in purple or violet eyes. People with albinism oftn have very light skin, hair, and eyes. Albinism is a genetic disorder that affects the production of melanin in the body. When the inflammation affects the iris, it can cause changes in the color of the eyes, including a purple or violet hue.Īlbinism is another condition that can result in purple eyes. This can happen due to various medical conditions, such as uveitis or iritis. When this mutation occurs in the eyes, it can result in a lack of pigmentation, leading to purple or violet eyes.Īnother reason for purple eyes is inflammation inside the eye. This mutation affects the production of melanin, which is responsible for giving color to our hair, skin, and eyes. It’s about the way the light enters and exits the eye, creating the appearance of blue, the same way the sky looks blue but outer space is not blue,” says Irizarry.One of the main causes of purple eyes is a genetic mutation. The lack of pigment causes the eye to appear blue. In humans, he says, blue eyes are caused by a genetic variation between a pair of genes called HERC2 and OCA2 in the human genome.Īccording to Irizarry, the mutation of the ALX4 gene in Siberian huskies seems to result in decreased pigment production in the eye. But for these breeds the blue-eyed trait is inherited as a recessive trait, meaning that two mutated copies of the gene are required for the blue eyes to occur. Read more about sled dogs here: "What Makes a Good Sled Dog?" Paths to Baby Blueīlue eyes are found in a number of dog breeds, including Old English sheepdogs, border collies, and Welsh and Pembroke corgis, Irizarrypoints out. These sled dogs aren't just the typical Siberian husky-some have been crossed with other breeds to go farther and faster. 31, 2015 - In West Yellowstone, Montana, sled dog mushers of all ages gather to compete in the Rodeo Run, a two-day race. “Genetics is this very complex spider web of pushes and pulls-and order and time are critical.” “One gene will turn on another, or turn off another, or turn off 10 and turn on others,” he says. Genes are all about cause and effect, like dominoes toppling over, says geneticist Kristopher Irizarry of the College of Veterinary Medicine at Western University of Health Sciences. Researchers found that a genetic change, or mutation, near a gene known as ALX4 on canine chromosome 18 is strongly associated with blue eyes in Siberian huskies. The size of the study was possible because of the scientists’ access to vast data thanks to the test kits purchased and owners’ willingness to participate in an online survey where they could also share photos of their dogs. Researchers tested the DNA of more than 6,000 dogs whose owners had purchased DNA test kits to confirm or identify their dogs’ breeds and explore their potential risk of health conditions. The study was published last week in the journal PLOS Genetics by Adam Boyko and Aaron Sams of Embark Veterinary, Inc. In the largest study ever to compare dogs’ complete genetic profiles, researchers found a genetic tweak that can cause blue-eyed dogs. Scientists at a DNA testing startup set out to explore the question by looking into other variations-besides coat color-that might cause blue eye color in dogs. But what about other dogs that sometimes have piercing baby blues, like the striking and popular Siberian husky? (Related: What Makes a Great Sled Dog? Breed, Ambition, Tough Feet.) Scientists know that blue eyes are related to the coat color of some dogs, like merle (or splotchy-coated) Australian shepherds. Scientists have thrown dog-lovers a bone: clues as to what causes this eye-catching trait. Elegant and expressive, blue-eyed dogs have some of the most unforgettable furry faces around.
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